Which of the following cells suggests that an immunologic response to plaque in the sulcus occurs in chronic inflammatory periodontal disease?
1. Mast cells.
2. Macrophages.
3. Plasma cells.
4. Neutrophils.
5. Lymphocytes.

(2) (3) (5)

(1) (2) (4)

(1) (3) (5)

(3) and (4)

(3) and (5)